BALR-6 regulates cell growth and cell survival in B-lymphoblastic leukemia
...Published in Molecular Cancer
MicroRNA-146a modulates B-cell oncogenesis by targeting Egr1
Published in Oncotarget
Long non-coding RNA in hematologic malignancies
Published in Briefings in Functional Genomics
Vectored Immunoprophylaxis Protects Humanized Mice from Mucosal HIV Transmission”
Published in Nature Medicine
Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-?B Gene Network
...Published in ” Cell Rep
“miRNA dysregulation in cancer: towards a mechanistic understanding”
Published in Frontiers in Genetics. Mar
Broad protection against influenza infection by vectored immunoprophylaxis in mice
Published in Nature Biotechnology
Neutralizing antibodies that target epitopes conserved among many strains of influenza virus have been recently isolated from humans. Here we demonstrate that adeno-associated viruses (AAV) encoding two such broadly neutralizing antibodies are protective against diverse influenza strains. Serum from mice that received a single intramuscular AAV inj...
MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice
Published in eLife
During inflammation and infection, hematopoietic stem and progenitor cells are stimulated to proliferate and differentiate into mature immune cells, especially of the myeloid lineage. MicroRNA-146a (miR-146a) is a critical negative regulator of inflammation. Deletion of miR-146a produces effects that appear as dysregulated inflammatory hematopoiesi...
A case of pediatric B-Lymphoblastic leukemia presenting with a t(9;12)(p24;q11.2) involving JAK2 and concomitant MLL rea...
Published in ” Biomark Res
MiR-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation
...Published in Cardiovascular & Hematological Agents in Medicinal Chemistry
